If you want to experience Wyland for free, his very large mural 'The Living Reef' can be seen half a block away from Key West harbor. It was originally painted as part of the Whaling Wall series of 100 (this is number 52) in September 1993. It was re-touched by him recently, in October 2012. It was looking very faded after 19 years and the re-touch has made it look much better.
You can see it at the old Waterfront Market, at Caroline and William Streets.
Other articles on this blog you might like:
Key West hotels - guide to where to stay and why you should seriously consider a B&B/guesthouse when you stay in Key West
Things to do Key West - my personal recommendations